Loeb's manuscript covers his ancestry, early life and schooling, and includes comments on bilingual upbringing. He documents his college education at Columbia University and University of Chicago, (Ph.D. in physics, 1916); World War I involvement and European contacts (1918-1919, Jean Baptiste Perrin and Ernest Rutherford); and his research fellowship at University of Chicago (1921). Loeb also discusses joining the U.S. Navy, and his appointment to the physics faculty at University of California, Berkeley (1923). Subjects discussed include the rebuilding of the Berkeley physics department; teaching and lecturing techniques; administrative and research work before and after World War II; and his naval promotion. Loeb also comments on other scientists (Ernest Rutherford in particular) and his collaborations; research production and scientific interests; his personal life; bookwriting; and consulting services. The supplement is a chronological account of conferences and travels (home and abroad). There are also comments, sometimes detailed, on thesis and other research work of some of his graduate students, and on the National Science Foundation lectures in 1970.