In this interview, Edward Uhler Condon discusses topics such as: his family background; early education; influence of high school physics teacher, William Howell Williams, 1914-1918, and later teacher at University of California, Berkeley; interval as boy reporter. Undergraduate years at Berkeley, beginning in 1921 in chemistry department; Ph.D. in physics, 1926; association with Fred Weinberg. Discovery of Erwin Schrd̲inger's wave mechanics papers; International Education Board fellowship to study quantum mechanics at Gt̲tingen, 1926. Work on Bell Systems technical journal for six months before accepting lectureship at Columbia University; teaching post at Princeton University; Condon and Philip Morse's Quantum Mechanics, result of Columbia and Princeton courses. Relations with University of California; role in persuading Ernest Lawrence to go to Berkeley from Yale University. Recollections of Michigan summer school. Work at Westinghouse on applications of nuclear physics to industry, including completion of Van de Graaff machine, 1937-1940; setting up Westinghouse research fellowships, 1938; Massachusetts Institute of Technology conference on applications of nuclear physics, October 1940; war work on microwave radar. J. Robert Oppenheimer asks Condon to come to Los Alamos Scientific Laboratory; tour of Los Alamos with Leslie Groves; reasons for leaving Los Alamos after a few weeks. Work as head of theoretical section of Lawrence's laboratory, August 1943-1945; British scientists. Evaluation of Westinghouse's four million-volt machine. Description of Nimitron, a physical computer, designed for 1939 World's Fair. Discussion of 1928 radioactivity. Reminiscences of Ronald Gurney's later career and his trouble with security. Discussion of postwar events, such as the Quebec Conference, McMahon Act, Moran's book about Winston Churchill. Peacetime development of atomic energy; establishment of the Senate's Special Committee on atomic energy. Directorship of the National Bureau of Standards (NBS), 1945-1951. Work on superconductivity; W. Emmanuel Maxwell and John Pelham. Accomplishments at NBS. Hearings in 1948 and 1952 before the Department of Commerce under Truman's loyalty program; Averell Harriman. Director of Research at Corning, 1951. House Un-American Activities Committee hearing, 1954; J. R. Oppenheimer and Bernard Peters; reopening of clearances, loss of Corning position; becomes Corning consultant. Head of Washington University physics department, 1956-1963; Oberlin College, 1962; interest in modernizing teaching; Joint Institute for Laboratory Astrophysics (JILA), from 1963; editor of Reviews of Modern Physics, 1957-1968; establishment of the National Accelerator Laboratory (Chicago); the UFO story. Comments on his most satisfying and his least satisfying work. Also prominently mentioned are: Raymond T. Birge and Henry Wallace.