In this interview, Sheldon Glashow, Professor of Physics Emeritus at Harvard University and Professor of Physics Emeritus at Boston University, reflects on his career and Nobel Prize winning work. He discusses his childhood friendship with Steve Weinberg and his passion for science from a young age. He reflects on his decision to attend Cornell University for undergrad and details the physics curriculum at the time. Glashow describes his time as a graduate student at Harvard University studying under Julian Schwinger. He discusses his time as a post-doc at the Institute for Theoretical Physics in Copenhagen working on the SU(2)XU(1) theory, which would later win him a Nobel prize in 1979. He speaks about working with Murray Gell-Mann while at Caltech and their collaboration on a paper together. Glashow details being hired as a full professor at Harvard University. He discusses his frequent collaboration with Alvaro De Rujula. He discusses the concept of string theory and how it has evolved over the years. He discusses the loss of the superconducting super collider and reflects on where particle and theoretical physics may be today had it been built. Lastly, Glashow reflects on his goals for "Inference: International Review of Science", of which he is the editor-at-large.