David Schramm discusses his family background; childhood reading of the encyclopedia; high school interest in athletics; flying model planes with father; early interest in great questions; religious background of parents; skepticism of organized religions; influence of uncles in decision to go to Massachusetts Institute of Technology (MIT); education at MIT; interest in math and physics; marriage in college; influence of Philip Morrison at MIT; experimental work in nuclear physics as an undergraduate; influence of Icko Iben; move to California Institute of Technology (Caltech) to work with William Fowler; early preference for steady state and oscillating universe models; work with Gerry Wasserburg on nuclear chronology; history of merger of cosmology with particle physics; work on big bang nucleosynthesis; work on supernovae; history of Schramm's work with Gunn and Steigman on limiting the number of neutrino types; early communication between particle physicists and cosmologists in the 1970s; more discussion of work on big bang nucleosynthesis; establishment of the big bang model; importance of grand unified theories in explaining the photon-to-baryon ratio; inflationary universe model and its dependence on baryogenesis; work on neutrino masses and dark matter; introduction to and attitude toward the horizon problem; attitude toward the inflationary universe model; change in attitude toward the horizon problem as a result of the inflationary universe model; introduction to the inflationary universe model; reasons why the inflationary universe model has been so widely accepted; crucial that inflationary model left many problems to be worked out; attitude toward the inflationary universe model; introduction to and attitude toward the flatness problem; work with Gunn and Tinseley on showing that the universe is open; reaction to de Lapparent, Geller, and Huchra's work on large-scale inhomogeneities; work of Kirshner et al., Kron and Koo on large-scale structure; importance of the availability of telescope time in determining what problems astronomers are interested in and working on; importance of looking for the background instead of simply the most unusual objects; importance of visual images; importance of interacting with others; interplay of theory and observation in cosmology; difficulty in showing whether inflation is right or not; new areas opened up in cosmology in the last decade; outstanding problems in cosmology: large-scale structure, dark matter, and galaxy formation, nature of the vacuum, phase transitions; ideal design of the universe; question of whether the universe has a point.