This interview begins with a discussion of Babcock's childhood and youth around Mt. Wilson Observatory, with comments on father (Harold D. Babcock), Walter S. Adams, and Edwin P. Hubble. Also discussed in this interview: education at Caltech, University of California at Berkeley and Lick Observatory (1934-1939), and at Yerkes and MacDonald Observatories; work at MIT and Caltech on World War II hardware; astronomical instrumentation work, especially postwar Mt. Wilson-Palomar diffraction gratings; discovery of magnetic stars and studies of variations; work on solar magnetic fields (with father) and theory of solar cycle; comments on cosmology; discussion of Mt. Wilson and Palomar Observatories since the 1920s, especially under Ira Bowen's and Babcock's directorship (1963); internal administration; staff relations; dealings with Carnegie Institution and Caltech; discussion of Hale Observatories, 1930-1977; role of government funding in astronomy; guest investigators; allocation of telescope time; planning, funding, and construction of the Carnegie Southern Observatory at Las Campanas, 1963-1977.

Also prominently mentioned are: Philip Abelson, Ed Ackerman, Carl David Anderson, Wilhelm Heinrich Walter Baade, Patrick Maynard Stuart Blackett, Vannevar Bush, Subrahmanyan Chandrasekhar, Crawford Greenewalt, Jesse Leonard Greenstein, George Ellery Hale, Caryl Haskins, Louis Henyey, Armin O. Leuschner, Nicholas Ulrich Mayall, Charles Edward Kenneth Mees, Paul Merrill, Rudolph Leo Bernhard Minkowski, Edgar Nichols, Elmer Prall, Bruce Rule, Frederick H. Seares, Sinclair Smith, Otto Struve, Charles Hard Townes, George van Biesbroeck, H. A. Wood, Fritz Zwicky; Astronomical Society of the Pacific, Astrophysical Journal, Bausch and Lomb Co., Eastman Kodak Co., Ford Foundation, Hale Observatories, Hale Solar Laboratory, Inyokern Project, Kitt Peak National Observatory, Las Campanas Observatory, Lick Observatory Bulletin, McDonald Observatory, Mount Wilson and Palomar Observatories, National Science Foundation (U.S.), 48-inch Schmidt Telescope, 100-inch Telescope, 120-inch Telescope, 200-inch Telescope, and University of California at Berkeley, CA.