Interview with Thomas Witten, Homer J. Livingston Professor, Emeritus, in the Department of Physics, James Franck Institute. Witten recounts his childhood in Maryland, Utah, and then Colorado, as his father, a medical doctor moved jobs, and he describes his undergraduate experience at Reed College and where majored in physics and where he benefited from excellent attention from the professors. He discusses his graduate work at UC San Diego, where he was advised by Shang Ma working on two-dimensional charged Bose gas research, and he describes his postdoctoral research at Princeton to work with John Hopfield. Witten conveys the exotic nature of Ken Wilsons ideas on renormalization during that time, and he explains the origins of soft matter physics as a distinct field and his work at Saclay before joining the faculty at the University of Michigan. He describes his subsequent research on pushing concepts of renormalization into polymers and related work on the Kondo effect. Witten explains his decision to join the research lab at Exxon, and he conveys Exxons emulation of Bell Labs as a place where he could pursue basic science within an industrial research lab, and where he could continue his work on polymers. He describes the downsizing of the lab and his decision to join the faculty at the University of Chicago, and his discusses his developing interests in buckyballs and capillary flow. Witten describes his affiliation with the James Franck Institute and its rich history, and he explains his current interests in granular materials, thin sheets, and colloidal rotation. At the end of the interview, Witten emphasizes the technological impact of fast video on soft matter physics and his interest in the physics of crumpling objects.