In this interview, David Zierler, Oral Historian for AIP, interviews Pier Oddone, currently a grape farmer in Sonoma County and formerly director of Fermilab. Oddone recounts his childhood in Peru and what life was like as the child of Italian immigrants. He describes his early interest in physics and he describes the circumstances leading to his decision to go to the Massachusetts Institute of Technology (MIT) for his undergraduate education. Oddone discusses his graduate work at Princeton University, where he worked on composite scattering and participated in experiments at the Princeton Penn Accelerator. He describes his postdoctoral work at Caltech where he conducted research under the direction of Alvin Tollestrup. Oddone explains his decision join a research group at Berkeley and his collaborative work at SLAC where he worked on the BC25 bubble chamber experiment and the Positron-Electron Project (PEP) machine at the Berkeley Lab. He explains the significance of the time projection chamber (TPC) project and the impact of superconducting super collider (SSC) planning on the field. Oddone discusses his work for the National Cancer Institute and his decision to move to Fermilab. He explains his involvement with the Tevatron project, his management of relations with the DOE, and the legacy of the B-Factory program. At the end of the interview, Oddone describes his advisory work since his retirement.