Interview with Zane Arp, director for Biomedical Physics at the FDA. Arp provides an organizational overview of where his office sits within the FDA and its key institutional partners throughout and beyond the federal government. He recounts his childhood in Texas and his undergraduate experience at Angelo State where he majored in chemistry. Arp explains his decision to pursue a PhD in physical chemistry at Texas A&M with a focus on quantum chemistry through spectroscopy, and he describes his postgraduate work at Los Alamos on laser-induced breakdown spectroscopy. He discusses his subsequent work at Wye Laboratories and Johnson Space Controls in support of the International Space Station. Arp describes his next job at GlaxoSmithKline to work on pharmaceutical development and where he grew into management leadership roles. He describes the opportunities that led to him joining the FDA and he describes his game plan for improving the biomedical device research and regulatory process. Arp explains why this is a long-term proposition and he describes how COVID has, and has not changed FDAs regulatory environment. At the end of the interview, he reflects on what shifts he been able to put in place so far at the FDA and why his office truly benefits from having a mission statement.